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Ichthyosis bullosa of Siemens is a type of familial, autosomal dominant ichthyosis, a rare skin disorder.〔Freedberg, et al. (2003). ''Fitzpatrick's Dermatology in General Medicine''. (6th ed.). McGraw-Hill. ISBN 0-07-138076-0.〕 It is also known as bullous congenital ichthyosiform erythroderma of Siemens or ichthyosis exfoliativa. It is a genetic disorder with no known cure which is estimated to affect about 1 in 500,000 people.〔Caputo, Ruggero and Tadini, Gianluca: (''Atlas of Genodermatoses'' ), Page 19, Published by Taylor & Francis, 2005, ISBN 1-84184-251-6〕 ==History== Ichthyosis bullosa of Siemens (IBS) was first described by the German dermatologist Hermann Werner Siemens in 1937 from his study of an affected family. 〔Siemens, H.W.: "Dichtung und Wahrheit ueber die Ichthyosis bullosa, mit Bemerkungen zur Systematik der Epidermolysen." Arch. Derm. Syph. 175: 590-608, 1937〕 In 1994 the gene causing IBS was discovered and it was also proved in the same year that ichthyosis exfoliativa is the same disease as IBS. 〔OMIM (Online Mendelian Inheritance in Man), Johns Hopkins University, (''Ichthyosis Bullosa of Siemens )〕 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Ichthyosis bullosa of Siemens」の詳細全文を読む スポンサード リンク
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